Mild to moderate espresso consumption is expounded to lower peril of death

Mild to moderate espresso consumption is expounded to lower peril of death

doi: 10.1093/eurjpc/zwac008.

On-line forward of print.

Judit Simon 
Kenneth Fung 
Zahra Raisi-Estabragh 
Nay Aung 
Mohammed Y Khanji 
Márton Kolossváry 
Béla Merkely 
Patricia B Munroe 
Nicholas C Harvey 
Stefan Ok Piechnik 
Stefan Neubauer 
Steffen E Petersen 
Pál Maurovich-Horvat 


Judit Simon et al.

Eur J Prev Cardiol.




To gaze the association of daily espresso consumption with all-goal and cardiovascular (CV) mortality and predominant CV outcomes. In a subgroup of participants who underwent cardiovascular magnetic resonance (CMR) imaging, we evaluated the association between customary espresso intake and cardiac building and absorb.


UK Biobank participants without clinically manifested coronary heart disease at the time of recruitment were included. Common espresso intake used to be labeled into 3 groups: zero, gentle-to-moderate (0.5-3 cups/day) and excessive (>3 cups/day). In the multivariate diagnosis, we adjusted for the predominant CV peril components.


We included 468,629 participants (56.2 ± 8.1 years, 44.2% male), 22.1% didn’t delight in espresso regularly, 58.4% had 0.5-3 cups per day and 19.5% had >3 cups per day. In contrast to non-espresso drinkers, gentle-to-moderate (0.5-3 cups per day) espresso drinking used to be connected to lower peril of all-goal mortality (multivariate HR = 0.88, 95%CI : 0.83-0.92; p < 0.001) and CV mortality (multivariate HR = 0.83, 95%CI : 0.74-0.94; p = 0.006), and incident stroke (multivariate HR = 0.79, 95%CI : 0.63-0.99 p = 0.037) after a median conform to-up of 11 years. CMR data were on hand in 30,650 participants. Every gentle-to-moderate and excessive espresso drinking classes were connected to dose-dependent elevated left and honest appropriate-looking ventricular end-diastolic, end-systolic and stroke volumes, besides to greater left ventricular mass.


Coffee consumption of up to a pair cups per day used to be connected to good CV outcomes. Common espresso consumption used to be also connected to a likely healthy pattern of CMR metrics in conserving with the reverse of age-connected cardiac alterations.

Key phrases:

Cardiac magnetic resonance; Cardiovascular health; Coffee consumption.

Equivalent articles

  • Consumption of espresso and tea and peril of growing stroke, dementia, and poststroke dementia: A cohort gaze within the UK Biobank.

    Zhang Y, Yang H, Li S, Li WD, Wang Y.
    Zhang Y, et al.
    PLoS Med. 2021 Nov 16;18(11):e1003830. doi: 10.1371/journal.pmed.1003830. eCollection 2021 Nov.
    PLoS Med. 2021.

    PMID: 34784347
    Free PMC article.

  • Coffee and tea consumption within the early adult lifespan and left ventricular feature in center age: the CARDIA gaze.

    Nwabuo CC, Betoko AS, Reis JP, Moreira HT, Vasconcellos HD, Guallar E, Cox C, Sidney S, Ambale-Venkatesh B, Lewis CE, Schreiner PJ, Lloyd-Jones D, Kiefe CI, Gidding SS, Lima JAC.
    Nwabuo CC, et al.
    ESC Coronary heart Fail. 2020 Aug;7(4): 1510-1519. doi: 10.1002/ehf2.12684. Epub 2020 May perchance perchance additionally merely 25.
    ESC Coronary heart Fail. 2020.

    PMID: 32449612
    Free PMC article.

  • Association of Coffee Inviting With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank.

    Loftfield E, Cornelis MC, Caporaso N, Yu Ok, Sinha R, Freedman N.
    Loftfield E, et al.
    JAMA Intern Med. 2018 Aug 1;178(8): 1086-1097. doi: 10.1001/jamainternmed.2018.2425.
    JAMA Intern Med. 2018.

    PMID: 29971434
    Free PMC article.

  • Prolonged-term espresso consumption and peril of cardiovascular disease: a systematic review and a dose-response meta-diagnosis of capacity cohort reports.

    Ding M, Bhupathiraju SN, Satija A, van Dam RM, Hu FB.
    Ding M, et al.
    Circulation. 2014 Feb 11;129(6): 643-59. doi: 10.1161/CIRCULATIONAHA.113.005925. Epub 2013 Nov 7.
    Circulation. 2014.

    PMID: 24201300
    Free PMC article.


  • Effects of ordinary espresso consumption on cardiometabolic disease, cardiovascular health, and all-goal mortality.

    O’Keefe JH, Bhatti SK, Patil HR, DiNicolantonio JJ, Lucan SC, Lavie CJ.
    O’Keefe JH, et al.
    J Am Coll Cardiol. 2013 Sep 17;62(12): 1043-1051. doi: 10.1016/j.jacc.2013.06.035. Epub 2013 Jul 17.
    J Am Coll Cardiol. 2013.

    PMID: 23871889


NOW WITH OVER +8500 USERS. of us can Be half of Knowasiak for free. Evaluation in on
Read More

Ava Chan

Ava Chan

I'm a researcher at Utokyo :) and a big fan of Ava Max