Mild to moderate espresso consumption is expounded to lower peril of death

doi: 10.1093/eurjpc/zwac008.

On-line forward of print.

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Judit Simon^1

2, Kenneth Fung^3

4, Zahra Raisi-Estabragh^3

4, Nay Aung^3

4, Mohammed Y Khanji^{3

4

5}, Márton Kolossváry¹, Béla Merkely¹, Patricia B Munroe³, Nicholas C Harvey⁶, Stefan Ok Piechnik⁷, Stefan Neubauer⁷, Steffen E Petersen^3

4, Pál Maurovich-Horvat^1

2

Affiliations

¹ MTA-SE Cardiovascular Imaging Analysis Crew, Semmelweis College, Budapest, Hungary.
² Medical Imaging Centre, Semmelweis College, Budapest, Hungary.
³ William Harvey Analysis Institute, NIHR Barts Biomedical Analysis Centre, Queen Mary College of London, London, United Kingdom.
⁴ Barts Coronary heart Centre, St Bartholomew’s Hospital, Barts NHS Trust, West Smithfield, London, United Kingdom.
⁵ Newham College Hospital. Glen Street, Plaistow, Barts Neatly being NHS Trust, London, United Kingdom.
⁶ MRC Lifecourse Epidemiology Unit, College of Southampton, Southampton, United Kingdom.
⁷ National Institute for Neatly being Analysis, Oxford Biomedical Analysis Centre, Division of Cardiovascular Medicine, Radcliffe Division of Medicine, College of Oxford, Oxford, United Kingdom.

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PMID:

35048949
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DOI:

10.1093/eurjpc/zwac008

Judit Simon et al.

Eur J Prev Cardiol.

2022.

doi: 10.1093/eurjpc/zwac008.

On-line forward of print.

Authors

Affiliations

¹ MTA-SE Cardiovascular Imaging Analysis Crew, Semmelweis College, Budapest, Hungary.
² Medical Imaging Centre, Semmelweis College, Budapest, Hungary.
³ William Harvey Analysis Institute, NIHR Barts Biomedical Analysis Centre, Queen Mary College of London, London, United Kingdom.
⁴ Barts Coronary heart Centre, St Bartholomew’s Hospital, Barts NHS Trust, West Smithfield, London, United Kingdom.
⁵ Newham College Hospital. Glen Street, Plaistow, Barts Neatly being NHS Trust, London, United Kingdom.
⁶ MRC Lifecourse Epidemiology Unit, College of Southampton, Southampton, United Kingdom.
⁷ National Institute for Neatly being Analysis, Oxford Biomedical Analysis Centre, Division of Cardiovascular Medicine, Radcliffe Division of Medicine, College of Oxford, Oxford, United Kingdom.

PMID:

35048949
DOI:

10.1093/eurjpc/zwac008

Summary

Aims:

To gaze the association of daily espresso consumption with all-goal and cardiovascular (CV) mortality and predominant CV outcomes. In a subgroup of participants who underwent cardiovascular magnetic resonance (CMR) imaging, we evaluated the association between customary espresso intake and cardiac building and absorb.

Techniques:

UK Biobank participants without clinically manifested coronary heart disease at the time of recruitment were included. Common espresso intake used to be labeled into 3 groups: zero, gentle-to-moderate (0.5-3 cups/day) and excessive (>3 cups/day). In the multivariate diagnosis, we adjusted for the predominant CV peril components.

Results:

We included 468,629 participants (56.2 ± 8.1 years, 44.2% male), 22.1% didn’t delight in espresso regularly, 58.4% had 0.5-3 cups per day and 19.5% had >3 cups per day. In contrast to non-espresso drinkers, gentle-to-moderate (0.5-3 cups per day) espresso drinking used to be connected to lower peril of all-goal mortality (multivariate HR = 0.88, 95%CI : 0.83-0.92; p < 0.001) and CV mortality (multivariate HR = 0.83, 95%CI : 0.74-0.94; p = 0.006), and incident stroke (multivariate HR = 0.79, 95%CI : 0.63-0.99 p = 0.037) after a median conform to-up of 11 years. CMR data were on hand in 30,650 participants. Every gentle-to-moderate and excessive espresso drinking classes were connected to dose-dependent elevated left and honest appropriate-looking ventricular end-diastolic, end-systolic and stroke volumes, besides to greater left ventricular mass.

Conclusion:

Coffee consumption of up to a pair cups per day used to be connected to good CV outcomes. Common espresso consumption used to be also connected to a likely healthy pattern of CMR metrics in conserving with the reverse of age-connected cardiac alterations.

Key phrases:

Cardiac magnetic resonance; Cardiovascular health; Coffee consumption.

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